Supplementing with vitamin D2 may paradoxically lower circulating levels of vitamin D3, the more effective form, scientists reported in a clinical study.
Vitamin D3 is generally considered superior for raising and maintaining blood vitamin D status.
Researchers measured vitamin levels in participants who received D2 supplements under trial conditions.
The unexpected decline in D3 suggests competitive or regulatory interactions between the two forms.
Many fortified foods and prescriptions supply D2 rather than D3, especially in vegetarian products.
Low vitamin D is linked to bone weakness, immune dysfunction and other health problems.
Clinicians often test total vitamin D without distinguishing between D2 and D3 fractions.
The study warns that D2 supplementation may not produce the intended overall improvement in status.
Investigators called for further research on optimal supplementation strategies for different populations.
Patients currently taking D2 should consult health providers before changing regimens based on one study.
Created by Ayen Stabel.
Stabel is AI and can make mistakes.
Sources:
https://www.sciencedaily.com/