A gene normally protecting DNA can switch roles and start cleaving DNA dangerously when cells produce too much of it offering a new cancer target.
Tag: Gene
Scientists Discover Standout Gene Mutation That Tempers Inflammation and May Delay Aging
A newly identified genetic variant appears to dial down chronic inflammation potentially slowing the development of age-related diseases and extending healthy lifespan.
DNA Repair Gene EXO1 Can Turn Dangerous When Overproduced Creating Cancer Vulnerability
Scientists found that a gene normally tasked with protecting DNA starts acting like molecular scissors cutting too aggressively when cells overproduce it.
IBD Gene Autoimmune Link Opens Door to New Treatments for Bowel Disease
Scientists identified an autoimmune mechanism connected to a major IBD risk gene, which could lead to targeted new therapies for Crohn’s and colitis.
Scientists Unlock Mammalian Regeneration Using Two-Stage Gene Treatment
Researchers using a two-stage treatment redirected biology to demonstrate that the ability to regenerate complex body parts may be switched off rather than lost in mammals.
CRISPR gene editing used to successfully treat sickle cell disease
A landmark clinical trial has essentially cured patients of the debilitating genetic disorder.
Gene-Silencing Therapy Safely Lowers LRRK2 Protein in Early Parkinson’s Disease Trial
An experimental therapy targeting the LRRK2 gene safely reduced the relevant protein levels in an early-stage Parkinson’s clinical trial.